Epigenetic dynamics during preimplantation development
نویسندگان
چکیده
منابع مشابه
Epigenetic Re-Programming during Mammalian Preimplantation Embryogenesis and Pgc Development
Abbreviations: PGCs: Primordial Germ Cells; XCI: X Chromosome Inactivation; 5mC: 5-methylcytosine; 5hmC: 5-hydroxymethylcytosine; Xp: Paternal X Chromosome; 5fC: 5-formylcytosine; 5caC: 5-carboxylcytosine; ICM: Inner Cell Mass; PRC2: Polycomb Repressive Complex 2; IAPs: Intracisternal-A-Particles; CGIs: CpG Islands; gDMRs: Germline Differently Methylated Regions; Xi: Inactive X Chromosome; qRT-...
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DNA methylation patterns were evaluated during preimplantation mouse development by analyzing the binding of monoclonal antibody to 5-methylcytosine (5-MeC) on metaphase chromosomes. Specific chromosome patterns were observed in each cell stage. A banding pattern predominated in chromosomes at the one-cell stage. Banding was replaced at the two-cell stage by an asymmetrical labeling of the sist...
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ژورنال
عنوان ژورنال: REPRODUCTION
سال: 2015
ISSN: 1470-1626,1741-7899
DOI: 10.1530/rep-15-0180